Growth Hormone
Ipamorelin
5mg
$89
Selective growth hormone secretagogue with minimal cortisol or prolactin side effects. Promotes GH pulses for lean muscle, fat loss, recovery, and sleep quality.
- Tested by Freedom Diagnostics — independent US lab
- COA published with every lot
- Shipped from the US
For in-vitro research use only. Not for human or veterinary consumption, diagnostic, or therapeutic use.
Ipamorelin is a selective pentapeptide growth hormone secretagogue that mimics ghrelin to stimulate pulsatile GH release from the pituitary. Unlike GHRP-2 or GHRP-6, ipamorelin does not significantly raise cortisol, prolactin, or appetite, making it one of the cleanest GH secretagogues available. It is frequently paired with CJC-1295 to amplify and extend GH pulses.
Ipamorelin binds the ghrelin receptor (GHS-R1a) in the pituitary and hypothalamus, triggering GH release via the phospholipase C/IP3 intracellular signaling pathway. Its selectivity comes from its inability to activate cortisol-releasing pathways that GHRP-2 and GHRP-6 engage. The resulting GH pulses stimulate IGF-1 production in the liver, driving downstream anabolic and regenerative effects.
- Molecular Formula
- C₃₈H₄₉N₉O₅
- Molecular Weight
- 711.9 g/mol
- Form
- Lyophilized pentapeptide powder
- Solubility
- Soluble in bacteriostatic water
- Dosage Range
- 200–300mcg per injection, 1–3x daily (research context)
- Plasma Half-Life
- ~2 hours
- Bioavailability
- ~80% subcutaneous
Certificate of analysis
Independent third-party report for the lot you receive — identity and purity. Available on request with your order; we'll email it back the same business day.
Cold-chain when required
Temperature-sensitive peptides ship with insulation and coolant. Store as indicated on the vial. Stability notes included with the order.
For research only
Sold for in-vitro research and laboratory use. Not for human or veterinary consumption. We don't advise on protocols or dosing.
- [01]
Ipamorelin: a selective growth hormone secretagogue
Raun K. et al. · European Journal of Endocrinology · 1998
Ipamorelin produced robust GH release comparable to GHRP-6 without the cortisol or prolactin elevation observed with other GHRPs.
- [02]
Growth hormone secretagogues and body composition
Nass R. et al. · Annals of Internal Medicine · 2008
GH secretagogue administration in healthy older adults increased lean body mass and reduced fat mass over 6 months.
- [03]
Ghrelin receptor agonists and sleep architecture
Frieboes R.M. et al. · Journal of Sleep Research · 1999
GH secretagogue administration enhanced slow-wave sleep duration and GH pulse amplitude in healthy male subjects.